How Are Cell Based Therapies Performed?

How Are Cell Based Therapies Performed?

Platelet rich plasma therapies and cell-based therapies derived from bone marrow and adipose tissue are giving hope to patients who suffer from conditions such as arthritis, low back pain and sports-related injuries for treating their chronic pain.

Regenerative medicine treatments involve the injection of healthy cells derived from the patient’s own body, known as autologous therapies, to the site of injury.  These therapies deliver a concentration of the body’s own unique healing cells, including platelets and adult stem cells, to help repair and support formation of new healthy tissue.

Currently, the U.S. Food and Drug Administration (FDA) does not allow physicians to use stem cell products derived from another person for orthopedic clinical use.  Practitioners who follow FDA guidelines only use the patient’s own cells derived from blood, bone marrow or adipose (fat) tissues with nothing more than minimal manipulation to treat orthopedic conditions such as spine and joint pain.

Before Treatment

The patient first undergoes a comprehensive medical evaluation to confirm the diagnosis.  This includes taking a complete medical history, performing a detailed physical examination and obtaining diagnostic tests such as MRI, X-ray, or any necessary blood tests.

The physician will review the patient’s overall health including medication intake, nutritional status and exercise level. Because the cells used are from the patient’s own body, it is important to ensure optimal health of these cells. Medications that can interfere with cellular function may be discontinued temporarily.

During Treatment

Regenerative cell-based therapies are typically performed in a doctor’s clinic. The first part of the procedure involves collecting the cells from the patient’s body through the following:

  • Platelet rich plasma is obtained through a simple blood draw from the arm.
  • Bone marrow-derived cells are drawn from the back side of the pelvic bone.  A local anesthetic will be used to keep the patient comfortable.  Pain medication or anxiety reducing medication may be used if necessary.
  • Adipose-derived cells are collected by obtaining a fat sample, usually from the abdomen or buttocks. This is also done using a local anesthetic to keep the patient comfortable.

For more detailed information on the different steps involved in these procedures, you can watch our YouTube channel on how PRP, bone marrow and adipose cell based therapies are prepared. 


After the collection, the blood or bone marrow are transferred to a centrifuge machine to isolate and concentrate the cells and healing molecules.  Adipose tissue is washed, rinsed and resized using a special FDA-cleared device.  When the cellular product is ready for injection, the physician will use an ultrasound or fluoroscopic (X-ray) guidance to precisely deliver the healing cells to the injured area in a safe and comfortable manner.


After the procedure, we observe our patients in the clinic to ensure there are no complications before they leave for home.  A responsible adult is required to drive the patient home.  As an outpatient procedure, there is no need for hospitalization or lengthy stay in rehabilitation facilities.

After Treatment

Soreness in the injection site can be expected for up to four days after the procedure.  Ice, or mild analgesics can be used to ease the discomfort.   Wearing a brace may help as well.  Patients can continue their regular medications except for non-steroidal anti-inflammatory medications such as ibuprofen and blood thinners. These medications may need to be temporarily discontinued, so it is important that you inform your physician if you are on any of these medications.

Most patients are able to resume normal activities within days. Patients will be prescribed a course of physical therapy to help assist the body in healing.

Healing takes time.  Pain may be reduced after a few weeks, however most patients will notice slow, gradual improvement within 3-4 months.

Minimally invasive regenerative cellular treatments using the patient’s own healing cells such as platelets or stem cells are being used to treat conditions that are traditionally managed with medications or surgery.  When performed by a qualified regenerative medicine specialist, patients can enjoy years of pain relief and increased activity.

Drs. Christopher J. Rogers and Mary A. Ambach of San Diego Orthobiologics Medical Group together have successfully treated thousands of patients with PRP and cell-based treatments for more than three decades. They are published authors and stem cell researchers.  Their facility in Carlsbad contains the most advanced Regenerative Medicine technology in San Diego and offers same day treatments with the highest level of safety and efficacy.

Treating Arthritis Pain with Platelet Rich Plasma Therapy

Treating Arthritis Pain with Platelet Rich Plasma Therapy

Most Americans will experience pain and stiffness from arthritis at some point in their lives.  Arthritis can affect any joint in the body, including the knee, hip, shoulder, back…even the fingers and toes.  

Osteoarthritis, commonly known as degenerative arthritis, is estimated to affect one in four U.S. adults, making it one of the most common medical conditions Americans will face.  It is a chronic joint disease that slowly degenerates the protective cartilage in your joints and causes chronic inflammation. It can be successfully treated with platelet rich plasma therapy, which heals injured tissues and decreases painful inflammation.

How Platelet Rich Plasma Therapy Works

There are different kinds of cells found in our blood.  Red blood cells, white blood cells and platelets all serve critical functions in the body.  These include carrying oxygen, fighting infection and repairing damaged tissues.

Platelets help to stop bleeding, but they also release growth factors and proteins that promote tissue repair and decrease inflammation. Platelet rich plasma therapy concentrates these important healing components and reintroduces them in the specific injured area to stimulate tissue repair.  Its powerful healing properties can improve the degenerative effects of osteoarthritis and stop its progression (1).

Is it Safe?

Platelet Rich Plasma is the most common orthobiologic used to treat orthopedic conditions.  Orthobiologics are cells and cellular molecules used to heal orthopedic injuries.  There are hundreds of research studies in the peer-reviewed medical literature showing the safety of this treatment for orthopedic conditions (2-13).

How Effective Are Platelet Rich Plasma Treatments for Joint Osteoarthritis?

High quality clinical studies have proven that PRP is more effective than standard treatments of exercise, steroid injections and hyaluronic acid (gel) injections.  PRP has been shown to improve pain and function in patients with knee osteoarthritis in particular. 

Several factors play a role in the successful outcome with these treatments, including the severity of the osteoarthritis, medical comorbidities, medications and the patient’s nutritional status. It is important to evaluate the patient as a whole to determine proper treatment and to support a positive outcome.

Dr. Christopher Rogers of San Diego Orthobiologics Group performed one of the first PRP treatments in San Diego in 2009, and SDOMG is proud to be the first clinic in San Diego—and third in the United States—to offer ENDORET PRGF therapy for the treatment of orthopedic conditions. Dr. Rogers and Dr. Mary Ambach have performed thousands of ultrasound-guided platelet rich plasma treatments. Many patients obtain successful results with their PRP treatments after just one treatment.

Sources:
  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959502/pdf/jpr-13-65.pdf
  2. https://www.sciencedirect.com/science/article/abs/pii/S0749806313010050
  3. https://www.sciencedirect.com/science/article/abs/pii/S0749806315003539
  4. https://bjsm.bmj.com/content/49/10/657.short
  5. https://link.springer.com/article/10.1186/s13018-017-0521-3
  6. https://www.sciencedirect.com/science/article/abs/pii/S0003999313012124
  7. https://journals.sagepub.com/doi/abs/10.1177/0363546512471299
  8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844477/pdf/epj-08-2115.pdf
  9. https://www.sciencedirect.com/science/article/abs/pii/S0749806316307800
  10. https://journals.sagepub.com/doi/abs/10.1177/0363546520909397
  11. https://link.springer.com/article/10.1007/s00590-020-02623-4
  12. https://www.sciencedirect.com/science/article/abs/pii/S0749806315006593

13.https://cdn.journals.lww.com/md-journal/FullText/2020/03130/Platelet_rich_plasma_versus_hyaluronic_acid_in_the.40.aspx

 

Important Practice Information: Coronavirus (COVID-19)

Important Practice Information: Coronavirus (COVID-19)

PATIENT SAFETY IS OUR TOP PRIORITY

San Diego Orthobiologics Medical Group is taking special precautions to prevent the spread of COVID-19 (coronavirus) infection.

In an effort to ensure safety of all patients and staff, we kindly ask that you contact the office to reschedule your appointments if you:

Are experiencing any of these symptoms of viral infection:

  • Fever > 100 ° F or chills
  • Difficulty breathing
  • Sore throat
  • Dry cough

Have within the last 2 weeks:

  • Been exposed to a patient with viral illness symptoms
  • Travelled to China, Iran, Italy, Japan or South Korea
  • Visited a nursing care facility

We have always taken a proactive and vigilant approach to ensure patient safety. We continue to sanitize our facility and equipment rigorously and take all necessary precautions to protect our patients and staff.

To slow transmission of the virus in our community:

  • Minimize touching surfaces when in public.
  • Wash hands frequently for more than 20 seconds.
  • Use CDC-approved hand sanitizers
  • Cover your mouth with your arm when coughing
  • Stand more than 6 feet away from people when in public
  • Reduce face-to-face contact with people known to have viral illness

For more information about coronavirus, please visit CDC coronavirus (COVID-19) information site

We all need to be mindful, not fearful. 

Don’t Miss: 30% OFF cell-based therapies

Don’t Miss: 30% OFF cell-based therapies

San Diego Orthobiologic Medical Group would like to help you get a jumpstart on your health.  We are offering a 30% discount our more advanced cell based therapies (*does not include PRP).

These are evidence based, non-surgical alternatives for arthritis, tendon tears and other orthopedic conditions.  

You can visit our website to learn more about bone marrow and adipose derived cell based therapies at https://sdomg.com.

This special is good for a limited time only, so call us now at (760) 909-2355 to schedule your evaluation.

Dr Chris Rogers lectured on Evidence Based Medicine at the IOF Annual Conference

Dr Chris Rogers lectured on Evidence Based Medicine at the IOF Annual Conference

Dr Rogers gave an outstanding presentation on what  institutes evidenced based medicine and who should decide. He shared his expertise on Orthobiologics to attendees consisting of scientists, fellow physicians and experts in the field of Interventional Orthopedics.

The San Diego Orthobiologics team participated in the  Interventional Orthopedics Foundation’s Annual Scientific Conference in Broomfield, Colorado. Dr. Rogers and Dr. Ambach learned new science and discussed research and ideas on Regenerative Medicine with scientists and physicians from all over the world.

dr-rogers-IOF

NextMed Center of Carlsbad – GRAND OPENING AND COMMUNITY EVENT

NextMed Center of Carlsbad – GRAND OPENING AND COMMUNITY EVENT

San Diego Orthogioloics is extremely excited to be opening the doors to the NexMed Center of Carlsbad.

The NextMed Center of Carlsbad medical campus is the hub for innovative medical treatments with an eye to defining the future of medicine. From women’s services to regenerative medicine; orthopedics to same-day surgery – the best doctors in the country have come together to serve patients in the beautiful sea-side town of Carlsbad.

Along with Dr. Christopher Rogers, the center will also have the following doctors available: Dr. Neil McKenna, FAAOMPT, OSC  & Dr. Min Kim, ND, LAc

Grand Opening & Community Event will include:

  • Hosted tours of medical suites, light refreshments and children’s activities
  • Street Tacos
  • Kona Ice Truck
  • Face Painting
  • Bounce House
  • DJ Simple rocking the tunes
  • Balloon Artist
  • Fresh Popcorn
  • Lemonade Stand

Doors will open to the public on Saturday, August 12th at 11 am to 2 pm, at 6125 Paseo del Norte, Carlsbad, CA 92011-1117

This is a FREE event and we hope to see you all there.

For information please contact us at 760-909-2355.

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