Jan 17, 2021
You may recall from your high school biology class that cells are referred to as the “building blocks of life”. When your body becomes injured or worn out, these building blocks break down leading to pain and loss of function. Yet, cellular therapy is the carpenter that repairs and replaces these broken cells and tissues.
Cell based therapy harnesses the powerful healing capabilities of cells in your body to repair damaged tissues and restore health. These are innovative therapies are based on concepts and scientific evidence that has emerged over the recent decades.
The world-renowned Center for Regenerative Medicine at the Mayo Clinic works closely with the Human Cellular Therapy Laboratories at campuses in Minnesota, Florida and Arizona to develop cellular therapies for more than a dozen medical conditions. These include ALS (Lou Gehrig’s disease), cancer, diabetes and orthopedic conditions such as osteoarthritis and degenerative disk disease [i]. San Diego Orthobiologics Medical Group is the premier regenerative medical center in San Diego providing therapies for orthopedic conditions. Drs. Christopher Rogers and Mary A. Ambach are recognized leaders in this field for their expertise in this exciting new medical specialty. Together, they have developed an extensive record of using Cell Based therapies to treat thousands of patients suffering from conditions such as painful arthritis or debilitating lower back pain. Many of these patients thought they had exhausted all of their treatment options and were concerned about resigning to a life of pain.
Cell Based therapies has given them a new lease on life.
All of the treatments offered at the San Diego Orthobiologics Medical Group are FDA-compliant and based on sound scientific evidence. We only use cells that are derived from the patient’s own body and processed in our state of the art laboratory using FDA-approved devices and methods. We do not use any donor stem cell products because these have not been tested for safety or efficacy.
These regenerative treatments contain restorative cells that are derived from a patient’s own blood, fat or bone marrow tissues. They help jump start the body’s own natural healing processes by encouraging the growth of healthy new cells and tissues to replace those that are injured or degenerated.
Dr. Christopher Rogers currently serves on the board of directors for the American College of Regenerative Medicine and has published and lectured extensively at national medical conferences on spine care, sports medicine, regenerative medicine and musculoskeletal ultrasound. He regularly teaches courses on regenerative cellular therapy throughout the country, including at the Regenerative Medicine Training Institute, the Interventional Orthopedics Foundation and the Orthobiologic Institute.
Dr. Mary A. Ambach is a clinical instructor at the University of California San Diego School of Medicine and also serves as a clinical instructor of medicine at the David Geffen School of Medicine at UCLA, clinical assistant professor of Physical Medicine & Rehabilitation at the Western University of Health Sciences and an associate professor at the Southern California University Sports Medicine Program. She has authored several published articles and book chapters in Regenerative Medicine and is actively involved in clinical research studying the effects of bone marrow-derived cells and platelet rich plasma for the treatment of low back pain due to degenerative disc disease.
Platelet rich plasma and other cell based therapies represent some of the most exciting advances seen in medicine in recent years. They offer patients options not previously available for conditions that were not previously treatable without surgery. Patients should do their homework and get the facts about how these treatments may help them to alleviate pain and restore a healthy, active life.
[i] https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/shared-services/human-cellular-therapy-laboratory
Jan 11, 2021
Join our free webinar to learn about non-surgical treatments and therapies for rotator cuff tendon injuries. Gain information on cutting edge treatments like platelet-rich plasma (PRP) and other cell-based therapies. Get answers to your questions from experts in the field of Regenerative Medicine.
Dr. Mary Ambach specializes in non-surgical orthopedics, regenerative therapies and interventional pain management. As a key thought leader in the field of Regenerative Medicine, Dr. Ambach conducts research, trains physicians and lectures at international medical conferences.
Dr. Christopher Rogers is one of the world’s leading experts in orthopedic regenerative medicine and a renowned speaker at national medical conferences. He has developed new approaches for the treatment of tendon injuries, osteoarthritis and disc degeneration which provide a safe and viable alternative to surgery.
Register for the Webinar HERE
Dec 30, 2020
ASK THE DOCS
Facebook Live Series
When: Every 1st Wednesday of the month at 12:30 PT
What: Live Question and Answer session with Regenerative Experts
Rotator Cuff Tendon Tear and Tendinopathy
Join us on January 6, 2021 at 12:30pm PT for our Free Facebook Live Series called Ask the Docs. In this session, SDOMG physician experts will answer your questions on this common shoulder problem and non-surgical options to treat it.
Dec 11, 2020
Natural therapies have been a valuable option for patients seeking alternative options to traditional medical treatments. These natural remedies can help relieve pain and stiffness associated with joint arthritis. It can also play an important role in one’s overall wellness.
Natural Ways to Reduce Joint Pain
Massage
Massage therapy has shown many health benefits for thousands of years. It can help improve flexibility, improve circulation, manage chronic pain, and improve rehabilitation. It can also promote overall well-being by reducing anxiety, promoting relaxation and improving sleep.
Acupuncture
Acupuncture is a form of traditional Chinese medicine which involves very thin small needles that are inserted through the skin at specific acupuncture points on the body. It is believed to stimulate the central nervous system, improve blood flow and activate the body’s natural painkillers. A meta-analysis study showed that acupuncture can not only improve chronic knee pain associated with osteoarthritis, it can also improve short and long term physical function.
Yoga
Yoga is an ancient Indian practice that uses deep breathing, meditation and body postures. Several studies have shown significant reduction in pain and function with improved strength, balance and gait, when used as an adjunct in the management of arthritis.1 The psychological benefits of Yoga therapy have been shown in the published literature to help reduce blood pressure, heart rate, anxiety and many other benefits.
Exercise
Exercise keeps your joints flexible and improves the strength of supporting muscles. Low impact exercises such as walking, cycling, and aquatic therapy are great options for patients with joint arthritis. Working with a physical therapist or a personal trainer offers many benefits in addition to getting proper exercise. They can perform manual therapies, counsel on proper positioning and body movement and recommend assistive devices such as braces. Aquatic therapy, also known as pool therapy or water therapy, is an alternative option for those who can not perform land-based therapies with less risk of exacerbating their joint pain. The gravity reduced environment of water can allow for gentle movements to improve strength, flexibility, and endurance that is better tolerated by some.
It is important to maintain a regular home exercise routine to continue the benefits of exercise and maintain overall health.
Weight loss
Being overweight is a major risk factor for the development of osteoarthritis. Losing weight removes extra pounds of pressure on swollen, painful joints. Maintain a healthy weight by combining a balanced diet with regular physical activity.
Heat and Cold
Heat can relieve muscle and joint stiffness while cold can reduce inflammation, swelling and pain. These are easily available modalities that can help manage joint pain and reduce the need for pain medications .
Natural alternative arthritis treatments are generally safe and can be a good adjunct to standard medical treatments. Some do have scientific evidence to support their efficacy, however others need more research to evaluate their benefits. Patients can discuss these treatments with their doctor to determine if these are appropriate for their specific needs.
1 Ebnezar J, Nagarathna R, Yogitha B, Nagendra HR. Effect of integrated yoga therapy on pain, morning stiffness and anxiety in osteoarthritis of the knee joint: A randomized control study. Int J Yoga. 2012;5(1):28-36. doi:10.4103/0973-6131.91708
Nov 17, 2020
Turmeric, a spice from South Asia derived from the Curcuma longa root, has been used as a medicine for nearly 4000 years. Recent studies have shown that turmeric may help to relieve joint pain caused by arthritis because the active ingredient, curcumin, is now known to have anti-inflammatory properties. Curcumin has been shown to have similar efficacy to diclofenac, a non-steroidal anti-inflammatory drug, with fewer side effects. Similar improvements in pain severity and function were seen with curcumin and diclofenac in a randomized, controlled clinical study of 139 patients with knee osteoarthritis. Nineteen patients in the diclofenac group (and none in the curcumin group) required anti-ulcer medications at 28 day followup [1].
Turmeric for Joint Pain Relief
Curcumin has also been shown to have a strong antioxidant capacity. In a randomized double-blind placebo-controlled trial, patients with mild-to-moderate knee osteoarthritis were given the curcuminoid and were compared to a group that received a placebo for 6 weeks. [2] Researchers measured the levels of enzymes known to influence inflammation (e.g. superoxide dismutase (SOD) and malondialdehyde (MDA)). The treatment group showed significant changes in these enzymes suggesting that short-term supplementation with curcumin decreases oxidative stress.
Another randomized, double-blind, placebo-controlled trial of low or high dose bio-optimized Curcuma longa in 150 patients with knee osteoarthritis measured serum biomarkers of cartilage degradation (sColl2-1). [3] The high dose extract showed a transient but non-significant decrease in the cartilage degradation biomarkers. Moreover, pain improvement in the low- and high-dose extracts was better than in the placebo group after 90 days of treatment.
The effects of topical curcumin 5% ointment on osteoarthritis knee pain in patients older than 70 years was studied in a double-blind, randomized placebo-controlled trial.[4] Subjects applied either the ointment or a placebo (Vaseline) twice a day for 6 weeks. The pain intensity was significantly lower in the group receiving the curcumin ointment than in the placebo group suggesting that this treatment may be considered for older adults with knee osteoarthritis.
[1] Shep D, Khanwelkar C, Gade P, Karad S. Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis: a randomized open-label parallel-arm study. Trial 2019; 20:214.
[2] Panahi Y, Alishiri GH, Parvin S, Sahebkar A. Mitigation of systemic oxidative stress by curcuminoids in osteoarthritis: results of a randomized controlled trial. J Dietary Suppl. 2016;13(2):209–20.
[3] Henrotin Y, Malaise M, Wittoek R, Vlam K, et al. Bio-optimized Curcuma longa extract is efficient on knee osteoarthritis pain: a double-blind multi center randomized placebo controlled three-arm study. Arthritis Research and Therapy 2019; 21, 179.
[4] Jamali N, Adib-Hajbaghery M, Soleimani A. The effect of curcumin ointment on knee pain in older adults with osteoarthritis: a randomized placebo trial. BMC Complementary Medicine and Therapies, 2020, 20:305.
Nov 13, 2020
We all know that sugar is an important ingredient in baking and cooking, but did you know that it also has important medicinal purposes? The simple sugar, dextrose, can be dissolved in solution and given intravenously to treat dehydration or administer medications.
In orthopedics, physicians use dextrose, which is a natural form of glucose, to promote the normal growth of cells and tissues. Proliferative therapy, commonly referred to as Prolotherapy, involves the injection of dextrose and water to the site of an injured tendon, ligament or joint to stimulate healing. It facilitates the restoration of strength and stability in these tissues.
The solution is prepared at varying concentrations of dextrose, combined with a local anesthesia to minimize discomfort. The concentrated dextrose serves as an irritant and triggers mild inflammation to jump start the natural healing process. Prolotherapy, when used in lower concentrations, has been shown to help nerve pain by blocking nerve pain impulses. It can be combined with natural homeopathic solutions to provide immediate relief to joint, nerve and other soft tissues.
Prolotherapy has been used to treat chronic musculoskeletal conditions for more than 80 years. It was developed by Dr. George Hackett in the 1950’s and represented a major step forward in identifying ways in which the body could heal itself naturally.
Conditions Treated with Prolotherapy
Prolotherapy can reduce pain and inflammation and improve healing in patients suffering from a number of orthopedic conditions, including:
- Tendinopathy
- Joint sprains or laxity
- Sacroiliac joint dysfunction
- Ligament sprains
- Osteoarthritis
- Plantar fasciosis
- Sports injuries such as tennis elbow or golf elbow
Prolotherapy is an Out-Patient Procedure
As opposed to oral medications that must work their way through the body’s systems to reach their intended target, prolotherapy is a targeted treatment that involves the injection of the medication directly to the injured body part. This is done using imaging guidance in the form of fluoroscopy (x-ray) or ultrasound. There is no incision, no major recovery time and no need for lengthy rehabilitation. The entire procedure takes less than an hour. There may be mild swelling or bruising for the first few days, however most patients are able to resume their normal activities the next day. To optimize healing and strengthening, patients are prescribed physical therapy and encouraged to maintain a healthy diet to ensure a successful outcome.
Drs. Christopher J. Rogers and Mary A. Ambach of San Diego Orthobiologics Medical Group together have successfully treated thousands of patients with regenerative therapies such as prolotherapy for more than three decades. They are published authors and cell therapy researchers. Their facility in Carlsbad contains the most advanced Regenerative Medicine technology in San Diego and offers same- day treatments with the highest level of safety and efficacy.
https://www.healthline.com/health/dextrose
